Protect Your Retina from light damage with the right light therapy. Some forms of light – like the white light in light boxes used in many light therapy devices, have been shown to cause retinal stress and damage. This is why wavelength matters. A more blue-turquoise light has been shown to be beneficial to the eye rather than harmful while still helping to reset the circadian clock rhythm. This study again shows that near infrared to red wavelength is protective and repairs light induced degeneration. Good reason to have red light along with the blue-turquoise of our eye mask.
Photobiomodulation protects the retina from light-induced photoreceptor degeneration.
PURPOSE:
In this study, the hypothesis that near-infrared (NIR) light treatment (photobiomodulation) attenuates bright-light damage in the albino rat retina was tested.
METHODS:
Young adult Sprague-Dawley (SD) albino rats were raised in dim (5 lux), cyclic light and then exposed to bright (1000 lux), continuous light for 24 hours. The animals were treated with 670-nm light (9 J/cm(2)) in an LED array before, during, or after exposure to light. The retinas were examined for function, structural changes, cell loss, and markers of stress and inflammation at 1 week and 1 month after exposure to damaging white light.
RESULTS:
Bright light caused photoreceptor-specific cell death in control retinas. Significant upregulation of stress and neuroprotective factors and the presence of activated microglia were also noted after light-induced damage. Photobiomodulation profoundly attenuated histopathologic alterations in all three treatment groups. NIR treatment also abolished microglial invasion of the retina and significantly reduced the presence of stress and neuroprotectant molecules. Bright-light-induced reductions in photoreceptor function were significantly ameliorated by photobiomodulation in animals treated before and during exposure to damaging light. Photoreceptor function was initially reduced in animals treated after bright-light-induced damage, but recovered by 1 month after exposure.
CONCLUSIONS:
NIR photobiomodulation is protective against bright-light-induced retinal degeneration, even when NIR treatment is applied after exposure to light. This protective effect appears to involve a reduction of cell death and inflammation. Photobiomodulation has the potential to become an important treatment modality for the prevention or treatment of light-induced stress in the retina. More generally, it could be beneficial in the prevention and treatment of retinal conditions involving inflammatory mechanisms.
- PMID:
- 21421867
- [PubMed – indexed for MEDLINE]